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NRSC 500

Module Four




Nov. 20
8:30-10:30

Nervous System Induction
Dr. Tim O’Connor

 

 

Reading:

Handout (of 2010)

Movies: Xenopus development




Nov. 22
8:30-10:30

Proliferation and migration
Dr. Daniel Goldowitz

 

 

Reading:

Lecture Notes (of 2011)

Lui J.H., Hansen D.V., Kriegstein A.R.: Development and Evolution of the Human Neocortex.
Cell 146 (2011), 18-36.

Manent J.B., Beguin S., Ganay T., Represa A.: Cell-autonomous and cell-to-cell signalling events in normal and altered neuronal migration. Eur. J. Neurosci. 34 (2011), 15951608.




Nov. 25
8:30-10:30

Process Outgrowth and Neural Pathfinding
Dr. Tim O’Connor

 

 

Reading:

Handout (2011)




Nov. 29
8:30-10:30

Synaptogenesis
Dr. Kurt Haas

 

 

Reading:

Washbourne P., Dityatev, A., Scheiffele P., Biederer T.,
Weiner J.A., Christopherson K.S.,
El-Husseini A.: Cell Adhesion Molecules in Synapse Formation.
J. Neurosci. 24 (2004), 9244-9249.

Kim E., Sheng M.:
PDZ domain proteins of synapses. Nat. Rev. Neurosci. 5 (2004), 771-781.

Goda Y., Davis G.W.:
Mechanisms of synapse assembly and disassembly.
Neuron 40 (2003), 243-264.

Sanes J.R., Lichtman J.W.:  Induction, assembly, maturation, and maintenance of a postsynaptic apparatus. Nat. Rev. Neurosci.
2 (2001), 791-805
.

Moss S.J., Smart T.G.:  Constructing inhibitory synapses.  Nat. Rev. Neurosci. 2 (2001), 240-250.




Nov. 27
8:30-10:30

Cell death in nervous system
Dr. Shernaz X. Bamji

 

 

Reading:

Handout (prev.)




Dec. 2
8:30-10:30

Activity and Circuit Formation
Dr. Kurt Haas

 

 

Reading:

TBA




Dec. 4
8:30-10:30

Student Presentations
Dr. Tim O’Connor and others

2-Page Critique Due

CIHR-Grant Assigment due




Dec. 9
8:30-10:30

FINAL EXAM
Room 2NA/B

 

 







 

 

 

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NRSC 500

NRSC 501

CPSC 532
(formerly
MECH 550)

STAT 540

Electives

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