DR. PETER F
LIDDLE
BSc (Hons),
BMBCh, PhD, FRCP(C)
Research
Description:
My laboratory is
engaged in the investigation of the cerebral
abnormalities associated with schizophrenia using
brain imaging techniques such as functional MRI,
PET, Electrical Event Related Potentials (ERPs) and
magnetoencephalography (MEG). Current studies
include:
- Examination
of the effects of atypical antipsychotics on
cerebral function in schizophrenia.
- Investigation
of functional connectivity between cerebral
areas in schizophrenia
- Delineating
the patterns of cerebral activity associated
with the characteristic symptoms of
schizophrenia.
Further details
are provided at our Neuroimaging
laboratory web-site
Selected
References:
Kiehl KA, Liddle
PF, Smith AM, Mendrek A, Forster BB, Hare RD. (in
press) Neural pathways involved in processing
concrete and abstract words. Human Brain
Mapping
Kiehl KA,
McDonald J, Hare R, Liddle PF. (in press) Reduced
P300 responses in criminal psychopaths during a
visual oddball task. Biological Psychiatry
McGuire PK;
Quested DJ; Spence SA; Murray RM; Frith CD; Liddle
PF (1998) Pathophysiology of 'positive' thought
disorder in schizophrenia. British Journal of
Psychiatry, 173, 231-235
Malizia AL;
Cunningham VJ; Bell CJ; Liddle PF; Jones T; Nutt DJ
(1998) Decreased brain GABA(A)-benzodiazepine
receptor binding in panic disorder - Preliminary
results from a quantitative PET study Archives of
General Psychiatry 55, 715-720
Baxter RD; Liddle
PF (1998) Neuropsychological deficits associated
with schizophrenic syndromes Schizophrenia Research
30, 239-249
Liddle PF (1997)
Dynamic neuroimaging with PET, SPET or fMRI
International Review of Psychiatry 9,
331-337
Spence SA; Brooks
DJ; Hirsch SR; Liddle PF; Meehan J; Grasby PM
(1997) A PET study of voluntary movement in
schizophrenic patients experiencing passivity
phenomena (delusions of alien control) Brain 120,
1997-2011
Chua SE; Wright
IC; Poline JB; Liddle PF; Murray RM; Frackowiak
RSJ; Friston KJ; McGuire PK (1997) Grey matter
correlates of syndromes in schizophrenia - A
semi-automated analysis of structural magnetic
resonance images British Journal of Psychiatry 170,
406-410
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