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FACULTY

GREGORY-EVANS


 
DR. CHERYL Y. GREGORY-EVANS

Bsc Pharmacology, UK; PhD University of Strathclyde, UK

 

Position: Associate Professor

Email:  email address

Department: Ophthalmology

Office: 604-875-5529

 

RESEARCH:

I have recently arrived from Imperial College London, UK
and my research interests can be found at:
http://www1.ic.ac.uk/medicine/people/k.gregory-evans/.

 

REFERENCES:

Xu, XL, Fang Y, Lee TC, Forrest D, Gregory-Evans CY, Almeida D, Liu A, Jhanwar SC, Abramson DH, Cobrinik D. Retinoblastoma has the properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling. Cell 2009;137:1018-31.

Moosajee M, Gregory-Evans K, Ellis C, Seabra MC, Gregory-Evans CY. Translational bypass of nonsense mutations in rep1, pax2.1 and lamb1 highlights a viable therapeutic option for untreatable genetic eye disease. Hum Mol Genet. 2008;17:3987-4000.

Gregory-Evans CY, Moosajee M, Hodges MD, Mackay DS, Game L, Vargesson N, Bloch-Zupan A, Ruschendorf F, Santos-Pinto L, Wackens G, Gregory-Evans K. SNP genome scanning localises oto-dental syndrome to chromosome 11q13 and microdeletions at this locus implicate FGF3 in dental and inner ear disease and FADD in ocular coloboma. Hum Mol Genet. 2007;16:2482-93.

Gregory-Evans CY; Vieira H; Dalton R; Adams GG; Salt A; Gregory-Evans K. Ocular coloboma and high myopia with Hirschsprung disease associated with a novel ZFHX1B missense mutation and trisomy 21. Am J Med Genet A. 2004;131:86-90.

Hodges MD, Bibb LC, Gregory-Evans K and Gregory-Evans CY. Characterisation of the genomic and transcriptional structure of the CRX gene: substantial differences between the human and mouse genes. Genomics 2002;80: 531-542.

Bibb LC, Holt JKL, Tarttelin EE, Hodges MD, Gregory-Evans K, Lucas RJ, Sowden JC and Gregory-Evans CY. Temporal and spatial expression patterns of the CRX gene and its downstream targets. Critical differences during human and mouse eye development. Hum Mol Genet 2001;10:1571-1579.

Freund CL, Gregory-Evans CY, Furukawa T, Papaioannou M, Looser J, Ploder L, Bellingham J, Ng D, Herbrick J-AS, Duncan A, Scherer SW, Tsui L-C, Loutradis-Anagnostou A, Cepko CL, Jacobson SG, Bhattacharya SS, and McInnes RR. Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) required for maintenance of the mammalian photoreceptor. Cell 1997;91:543-553.

 



 

 

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