Bsc Pharmacology, UK; PhD University of Strathclyde, UK
Position: Associate Professor
I have recently arrived from Imperial College London, UK
and my research interests can be found at:
Xu, XL, Fang Y, Lee TC, Forrest D, Gregory-Evans CY, Almeida D,
Liu A, Jhanwar SC, Abramson DH, Cobrinik D. Retinoblastoma has the
properties of a cone precursor tumor and depends upon cone-specific MDM2
signaling. Cell 2009;137:1018-31.
Moosajee M, Gregory-Evans K, Ellis C, Seabra MC, Gregory-Evans CY.
Translational bypass of nonsense mutations in rep1, pax2.1 and lamb1
highlights a viable therapeutic option for untreatable genetic eye disease.
Hum Mol Genet. 2008;17:3987-4000.
Gregory-Evans CY, Moosajee M, Hodges MD, Mackay DS, Game L, Vargesson N,
Bloch-Zupan A, Ruschendorf F, Santos-Pinto L, Wackens G, Gregory-Evans K.
SNP genome scanning localises oto-dental syndrome to chromosome 11q13 and
microdeletions at this locus implicate FGF3 in dental and inner ear disease
and FADD in ocular coloboma. Hum Mol Genet. 2007;16:2482-93.
Gregory-Evans CY; Vieira H; Dalton R; Adams GG; Salt A; Gregory-Evans K.
Ocular coloboma and high myopia with Hirschsprung disease associated with a
novel ZFHX1B missense mutation and trisomy 21. Am J Med Genet A.
Hodges MD, Bibb LC, Gregory-Evans K and Gregory-Evans CY. Characterisation
of the genomic and transcriptional structure of the CRX gene: substantial
differences between the human and mouse genes. Genomics 2002;80: 531-542.
Bibb LC, Holt JKL, Tarttelin EE, Hodges MD, Gregory-Evans K, Lucas RJ,
Sowden JC and Gregory-Evans CY. Temporal and spatial expression patterns of
the CRX gene and its downstream targets. Critical differences during human
and mouse eye development. Hum Mol Genet 2001;10:1571-1579.
Freund CL, Gregory-Evans CY, Furukawa T, Papaioannou M, Looser J, Ploder L,
Bellingham J, Ng D, Herbrick J-AS, Duncan A, Scherer SW, Tsui L-C,
Loutradis-Anagnostou A, Cepko CL, Jacobson SG, Bhattacharya SS, and McInnes
RR. Cone-rod dystrophy due to mutations in a novel photoreceptor-specific
homeobox gene (CRX) required for maintenance of the mammalian photoreceptor.